Search on: 3-PYRIDINECARBOXYLIC ACID, 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-(TRIFLUOROMETHYL)PHENYL)-, METHYL ESTER 
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Descriptor English:   3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester 
Descriptor Spanish:   Ácido 3-piridinacarboxílico, 1,4-dihidro-2,6-dimetil-5-nitro-4-(2-(trifluorometil)fenil)-, Éster Metílico 
Descriptor Portuguese:   Éster Metílico do Ácido 3-Piridinacarboxílico, 1,4-diidro-2,6-dimetil-5-nitro-4-(2-(trifluormetil)fenil) 
Tree Number:   D03.383.725.203.600
D03.383.725.547.900
Definition English:   A dihydropyridine derivative, which, in contrast to NIFEDIPINE, functions as a calcium channel agonist. The compound facilitates Ca2+ influx through partially activated voltage-dependent Ca2+ channels, thereby causing vasoconstrictor and positive inotropic effects. It is used primarily as a research tool. 
Indexing Annotation English:   a calcium channel agonist
Pharmacological Action:   Calcium Channel Agonists
 
History Note English:   87 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects agonists
antagonists & inhibitors analysis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
diagnostic use economics
history immunology
isolation & purification metabolism
pharmacology pharmacokinetics
poisoning radiation effects
supply & distribution standards
toxicity therapeutic use
urine  
Record Number:   23220 
Unique Identifier:   D001498 

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